Written By: Janel Miller, Healio.com
Flow Formula, a botanical blend containingCBD, was as effective as ibuprofen in relieving menstrual pain symptoms, according to results of a randomized, placebo-controlled, double-blinded trial.
Allen Morgan,MD,a reproductive endocrinologist and infertility specialist in Lakewood, New Jersey, told Healio Primary Care that he developed Flow Formula (cannabidiol botanical blend, Maxine & Morgan) after his daughter developed an ulcer from using NSAIDs for severe menstrual cramps. In addition to CBD, the product containsturmeric, ginger, cramp bark, fennel seed and valerian root. The ingredients were selected based on data from previous randomized controlled studies, Morgan said.
For the current analysis, Morgan and colleagues from the Hackensack Meridian Health Jersey Shore University Medical Center and Morgan Fertility and Reproductive Medicine randomly assigned 71 women to receive the cannabidiol botanical blend, ibuprofen or placebo for the first 4 days of three menstrual cycles. Among the participants, 51 completed numeric rating scales for pain before and after receiving the study drug, as well as a quality-of-life survey and questionnaire about symptom severity.
The results, which were presented at the virtual American College of Obstetricians and Gynecologists Annual Clinical and Scientific Meeting, showed that women who received the cannabidiol botanical blend reported similar reductions in pain scores compared with those who received ibuprofen. On day 1, thecannabidiol botanical blend was significantly more effective than ibuprofen and placebo in reducing nausea, according to the researchers. By day 3, the cannabidiol botanical blend was significantly more effective in reducing cramping, irritability and moodiness than the other two treatments. No adverse events were reported.
“There is an alternative to nonsteroidal anti-inflammatories that is easier on the tummy and reduces the symptoms of premenstrual syndrome and menstrual symptoms,” Morgan said.
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